SOD2 Antibody

• Background:

  SOD2 is a member of the iron/manganese superoxide dismutase family. It is a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer.

• NCBI Gene ID:

  6648

• Swiss Prot:

  P04179

• Accession Number:

  P04179

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SOD2 antibody is generated from rabbits immunized with human recombinant SD protein.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Obesity, Neuroscience, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  25 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  SOD2

• NCBI Official Name:

  Superoxide dismutase [Mn], mitochondrial

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Fabre, E.E., Am. J. Clin. Nutr. 87 (5), 1504-1512 (2008) Kaewpila, S., Cancer Res. 68 (8), 2781-2788 (2008) Flekac, M., (er) BMC Med. Genet. 9, 30 (2008)

• Other Product Names:

  Superoxide dismutase [Mn], mitochondrial, SOD2

• Tested Applications:

  WB, Flow

• Protein ID:

  134665

• Physical Properties:

  Liquid