F11 (NM_028066) Mouse Recombinant Protein

• Background:

  This gene encodes a glycoprotein coagulation factor that plays an important role in intrinsic pathway of blood coagulation and hemostasis. The encoded protein is an inactive zymogen that can be activated by coagulation factor XIIa, thrombin or factor XIa to generate active factor XIa protease. Mice lacking the encoded protein display a survival advantage during peritoneal sepsis and resist inflammation and bacterial accumulation upon infection with Listeria. [provided by RefSeq, Apr 2015]

• Synonyms:

  1600027G01Rik; AI503996; Cf11; FX; FXI; PTA

• Gene ID:

  109821

• UniProt:

  Q91Y47

• Accession Number mRNA:

  NM_028066

• Chromosomal Location:

  8 25.14 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  69.8 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  F11

• Species:

  Mouse

• Protein ID:

  NP_082342

• Overview:

  Purified recombinant protein of Mouse coagulation factor XI (F11), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/109821

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q91Y47

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_028066

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_082342