AP2 alpha (TFAP2A) (NM_001032280) Human Recombinant Protein

• Background:

  The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS) . Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009]

• Synonyms:

  AP-2; AP-2alpha; AP2TF; BOFS; TFAP2

• Gene ID:

  7020

• UniProt:

  P05549

• Accession Number mRNA:

  NM_001032280

• Chromosomal Location:

  6p24.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Activity:

  27866707

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Transcription Factors

• Molecular Weight:

  47 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  TFAP2A

• Species:

  Human

• Protein ID:

  NP_001027451

• Overview:

  Recombinant protein of human transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) (TFAP2A), transcript variant 2

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/7020

• Uniprot URL:

  https://www.uniprot.org/uniprot/P05549

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001032280

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001027451