Tfap2a (NM_011547) Mouse Recombinant Protein

• Background:

  This gene is a member of the activator protein 2 (AP-2) transcription factor family. The protein encoded by this gene can act as both an activator and repressor of gene transcription, and plays an important role in early embryogenesis, specifically in cranial development. This protein forms both homodimers and heterodimers, and binds to a GC-rich consensus sequence found in some promoters and enhancers. Disruption of this gene causes perinatal death, with neural tube, craniofacial, and limb mesenchyme defects. Alternative splicing results in multiple transcript variants that encode multiple protein isoforms. [provided by RefSeq, Sep 2014]

• Synonyms:

  A; AP; AP-2; Ap-2 (a) ; Ap2; AP2alpha; Ap2tf; Tcfa; Tcfap2a

• Gene ID:

  21418

• UniProt:

  P34056, Q8BPN4, A0A0R4J1E6, Q3UL09

• Accession Number mRNA:

  NM_011547

• Chromosomal Location:

  13 20.01 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  48.4 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Tfap2a

• Species:

  Mouse

• Protein ID:

  NP_035677

• Overview:

  Purified recombinant protein of Mouse transcription factor AP-2, alpha (Tfap2a), transcript variant 1a, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/21418

• Uniprot URL:

  https://www.uniprot.org/uniprot/P34056

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_011547

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_035677