MIF (NM_002415) Human Recombinant Protein

• Background:

  This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways. [provided by RefSeq, Jul 2008]

• Synonyms:

  GIF; GLIF; MMIF

• Gene ID:

  4282

• UniProt:

  P14174, I4AY87

• Accession Number mRNA:

  NM_002415

• Chromosomal Location:

  22q11.23

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Phenylalanine metabolism, Tyrosine metabolism

• Field of Research:

  Phenylalanine metabolism, Tyrosine metabolism

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  12.3 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  MIF

• Species:

  Human

• Protein ID:

  NP_002406

• Overview:

  Recombinant protein of human macrophage migration inhibitory factor (glycosylation-inhibiting factor) (MIF)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/4282

• Uniprot URL:

  https://www.uniprot.org/uniprot/P14174

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_002415

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_002406