CIPC (NM_033426) Human Recombinant Protein

• Background:

  Transcriptional repressor which may act as a negative-feedback regulator of CLOCK-ARNTL/BMAL1 transcriptional activity in the circadian-clock mechanism. May stimulate ARNTL/BMAL1-dependent phosphorylation of CLOCK. However, the physiogical relevance of these observations is unsure, since experiments in an animal model showed that CIPC is not critially required for basic circadian clock.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  KIAA1737

• Gene ID:

  85457

• UniProt:

  Q9C0C6

• Accession Number mRNA:

  NM_033426

• Chromosomal Location:

  14q24.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  42.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  CIPC

• Species:

  Human

• Protein ID:

  NP_219494

• Overview:

  Recombinant protein of human KIAA1737 (KIAA1737)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/85457

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9C0C6

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_033426

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_219494