Cipc (NM_173735) Mouse Recombinant Protein

• Background:

  Transcriptional repressor which may act as a negative-feedback regulator of CLOCK-ARNTL/BMAL1 transcriptional activity in the circadian-clock mechanism. May stimulate ARNTL/BMAL1-dependent phosphorylation of CLOCK (PubMed:17310242, PubMed:19414601) . However, the physiogical relevance of these observations is unsure, since experiments in knockout mice showed that CIPC is not critially required for basic circadian clock (PubMed:25862660) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  2310044G17Rik; AI842544; AI853744; Kiaa1737; mKIAA1737

• Gene ID:

  217732

• UniProt:

  Q8R0W1, Z4YJJ0

• Accession Number mRNA:

  NM_173735

• Chromosomal Location:

  12 D2

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  42.4 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Cipc

• Species:

  Mouse

• Protein ID:

  NP_776096

• Overview:

  Purified recombinant protein of Mouse CLOCK interacting protein, circadian (Cipc), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/217732

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q8R0W1

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_173735

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_776096