VPS26C (NM_006052) Human Recombinant Protein

• Background:

  The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and cognitive disability. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined. [provided by RefSeq, Jul 2008]

• Synonyms:

  DCRA; DSCR3; DSCRA

• Gene ID:

  10311

• UniProt:

  O14972

• Accession Number mRNA:

  NM_006052

• Chromosomal Location:

  21q22.13

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  32.8 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  VPS26C

• Species:

  Human

• Protein ID:

  NP_006043

• Overview:

  Recombinant protein of human Down syndrome critical region gene 3 (DSCR3)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/10311

• Uniprot URL:

  https://www.uniprot.org/uniprot/O14972

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_006052

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_006043