Guca2b (NM_008191) Mouse Recombinant Protein

• Background:

  This gene encodes a member of the guanylin family and preproprotein that is proteolytically processed to generate a mature protein product. The mature protein product, known as uroguanylin, is an endogenous ligand for the guanylate cyclase-C receptor and may regulate salt and water homeostasis in the intestine and kidneys. Homozygous knockout mice for this gene exhibit impaired sodium chloride excretion and elevated arterial pressure. This gene is present in a gene cluster with a related guanylin family member on chromosome 4. [provided by RefSeq, Sep 2015]

• Synonyms:

  AV066530; Gca; Gcap2; Ugn; urog

• Gene ID:

  14916

• UniProt:

  O09051, Q9QUQ3

• Accession Number mRNA:

  NM_008191

• Chromosomal Location:

  4 55.48 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  11.6 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Guca2b

• Species:

  Mouse

• Protein ID:

  NP_032217

• Overview:

  Purified recombinant protein of Mouse guanylate cyclase activator 2b (retina) (Guca2b), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/14916

• Uniprot URL:

  https://www.uniprot.org/uniprot/O09051

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_008191

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_032217