Uroguanylin (GUCA2B) (NM_007102) Human Recombinant Protein

• Background:

  This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products, including uroguanylin, a member of the guanylin family of peptides and an endogenous ligand of the guanylate cyclase-C receptor. Binding of this peptide to its cognate receptor stimulates an increase in cyclic GMP and may regulate salt and water homeostasis in the intestine and kidneys. [provided by RefSeq, Nov 2015]

• Synonyms:

  GCAP-II; UGN

• Gene ID:

  2981

• UniProt:

  Q16661

• Accession Number mRNA:

  NM_007102

• Chromosomal Location:

  1p34.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Secreted Protein, Transmembrane

• Molecular Weight:

  11.9 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  GUCA2B

• Species:

  Human

• Protein ID:

  NP_009033

• Overview:

  Recombinant protein of human guanylate cyclase activator 2B (uroguanylin) (GUCA2B)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/2981

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q16661

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_007102

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_009033