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Copz1 (BC025041) Mouse Recombinant Protein

CAT: 0882-PM48699M5Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0882-PM48699M5Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse coatomer protein complex, subunit zeta 1 (cDNA clone MGC:37172 IMAGE:4954031), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
5930435A22Rik; AA407760; D4Ertd360e
Gene ID
56447
UniProt
P61924
Accession Number mRNA
BC025041
Chromosomal Location
15 58.74 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
18.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Copz1
Species
Mouse
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/56447
Uniprot URL
https://www.uniprot.org/uniprot/P61924
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/BC025041

UniProtKB · P61924

Coatomer subunit zeta-1

COPZ1_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
P61924
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Copz1
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q9Y3C3
Protein keywords

Technical term

3D-structureReference proteome

PTM

Acetylation

Cellular component

CytoplasmCytoplasmic vesicleGolgi apparatusMembrane

Biological process

ER-Golgi transportProtein transportTransport