Dcun1d5 (NM_029775) Mouse Recombinant Protein

• Background:

  Contributes to the neddylation of all cullins by transfering NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes which is necessary for the activation of cullin-RING E3 ubiquitin ligases (CRLs) . May play a role in DNA damage response and may participate to cell proliferation and anchorage-independent cell growth.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  3110001A18Rik; 4833420K19Rik; AW060460; D430047L21Rik

• Gene ID:

  76863

• UniProt:

  Q9CXV9

• Accession Number mRNA:

  NM_029775

• Chromosomal Location:

  9 A1

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  27.6 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Dcun1d5

• Species:

  Mouse

• Protein ID:

  NP_084051

• Overview:

  Purified recombinant protein of Mouse DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae) (Dcun1d5), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/76863

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9CXV9

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_029775

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_084051