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E2f5 (NM_007892) Mouse Recombinant Protein

CAT: 0882-PM47173M5Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0882-PM47173M5Size:20 µg
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Background
Transcriptional activator that binds to E2F sites, these sites are present in the promoter of many genes whose products are involved in cell proliferation. May mediate growth factor-initiated signal transduction. It is likely involved in the early responses of resting cells to growth factor stimulation. Specifically required for multiciliate cell differentiation: together with MCIDAS and E2F5, binds and activate genes required for centriole biogenesis.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse E2F transcription factor 5 (E2f5), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
AU024671; E2F-5
Gene ID
13559
UniProt
Q61502
Accession Number mRNA
NM_007892
Chromosomal Location
3 A1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
36.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
E2f5
Species
Mouse
Protein ID
NP_031918
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/13559
Uniprot URL
https://www.uniprot.org/uniprot/Q61502
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_007892
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_031918

UniProtKB · Q61502

Transcription factor E2F5

E2F5_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
Q61502
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
E2f5
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
E2F-5
EC number
—
Processing
—
Secondary accessions
Q99LK0
Protein keywords

Molecular function

ActivatorDNA-binding

Biological process

Cilium biogenesis/degradationTranscriptionTranscription regulation

Cellular component

Nucleus

Technical term

Reference proteome

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