Malabaricone B

• Description :

  Malabaricone B, a naturally occurring plant phenolic, is an orally active α-glucosidase inhibitor with an IC50 of 63.7 μM. Malabaricone B has anticancer, antimicrobial, anti-oxidation and antidiabetic activities[1][2][3].

• UNSPSC :

  12352005

• Target :

  Apoptosis; Glycosidase

• Type :

  Natural Products

• Related Pathways :

  Apoptosis; Metabolic Enzyme/Protease

• Applications :

  Metabolism-sugar/lipid metabolism

• Field of Research :

  Cancer; Infection; Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/malabaricone-b.html

• Purity :

  99.58

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  O=C(C1=C(O)C=CC=C1O)CCCCCCCCC2=CC=C(O)C=C2

• Molecular Formula :

  C21H26O4

• Molecular Weight :

  342.43

• References & Citations :

  [1]Mrityunjay Tyagi, et al. Spice-derived phenolic, malabaricone B induces mitochondrial damage in lung cancer cells via a p53-independent pathway. Food Funct. 2018 Nov 14;9 (11) :5715-5727.|[2]K Y Orabi, et al. Isolation and characterization of two antimicrobial agents from mace (Myristica fragrans) . J Nat Prod. May-Jun 1991;54 (3) :856-9. |[3]B Prabha, et al. Antidiabetic potential of phytochemicals isolated from the stem bark of Myristica fatua Houtt. var. magnifica (Bedd.) Sinclair. Bioorg Med Chem. 2018 Jul 23;26 (12) :3461-3467.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [63335-24-0]