Malabaricone B

CAT: 0804-HY-N8517-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N8517-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Malabaricone B, a naturally occurring plant phenolic, is an orally active α-glucosidase inhibitor with an IC50 of 63.7 μM. Malabaricone B has anticancer, antimicrobial, anti-oxidation and antidiabetic activities[1][2][3].
CAS Number
[63335-24-0]
UNSPSC
12352005
Target
Apoptosis; Glycosidase
Type
Natural Products
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cancer; Infection; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/malabaricone-b.html
Purity
99.58
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=C(O)C=CC=C1O)CCCCCCCCC2=CC=C(O)C=C2
Molecular Formula
C21H26O4
Molecular Weight
342.43
References & Citations
[1]Mrityunjay Tyagi, et al. Spice-derived phenolic, malabaricone B induces mitochondrial damage in lung cancer cells via a p53-independent pathway. Food Funct. 2018 Nov 14;9 (11) :5715-5727.|[2]K Y Orabi, et al. Isolation and characterization of two antimicrobial agents from mace (Myristica fragrans) . J Nat Prod. May-Jun 1991;54 (3) :856-9. |[3]B Prabha, et al. Antidiabetic potential of phytochemicals isolated from the stem bark of Myristica fatua Houtt. var. magnifica (Bedd.) Sinclair. Bioorg Med Chem. 2018 Jul 23;26 (12) :3461-3467.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported