Malabaricone B

• Description:

  Malabaricone B, a naturally occurring plant phenolic, is an orally active α-glucosidase inhibitor with an IC50 of 63.7 μM. Malabaricone B has anticancer, antimicrobial, anti-oxidation and antidiabetic activities[1][2][3].

• UNSPSC:

  12352005

• Target:

  Apoptosis; Glycosidase

• Type:

  Natural Products

• Related Pathways:

  Apoptosis; Metabolic Enzyme/Protease

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Cancer; Infection; Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/malabaricone-b.html

• Purity:

  99.58

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C (C1=C (O) C=CC=C1O) CCCCCCCCC2=CC=C (O) C=C2

• Molecular Formula:

  C21H26O4

• Molecular Weight:

  342.43

• References & Citations:

  [1]Mrityunjay Tyagi, et al. Spice-derived phenolic, malabaricone B induces mitochondrial damage in lung cancer cells via a p53-independent pathway. Food Funct. 2018 Nov 14;9 (11) :5715-5727.|[2]K Y Orabi, et al. Isolation and characterization of two antimicrobial agents from mace (Myristica fragrans) . J Nat Prod. May-Jun 1991;54 (3) :856-9. |[3]B Prabha, et al. Antidiabetic potential of phytochemicals isolated from the stem bark of Myristica fatua Houtt. var. magnifica (Bedd.) Sinclair. Bioorg Med Chem. 2018 Jul 23;26 (12) :3461-3467.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  63335-24-0