Elmo1 (BC031782) Mouse Recombinant Protein

• Background:

  Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1 (By similarity) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  CED-12, 6330578D22Rik

• Gene ID:

  140580

• UniProt:

  Q8BPU7

• Accession Number mRNA:

  BC031782

• Chromosomal Location:

  13 A2

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  93.1 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Elmo1

• Species:

  Mouse

• Overview:

  Purified recombinant protein of Mouse engulfment and cell motility 1, ced-12 homolog (C, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/140580

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q8BPU7

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/BC031782