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Elmo1 (BC031782) Mouse Recombinant Protein

CAT: 0882-PM46517M5Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0882-PM46517M5Size:20 µg
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Background
Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1 (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse engulfment and cell motility 1, ced-12 homolog (C, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
CED-12, 6330578D22Rik
Gene ID
140580
UniProt
Q8BPU7
Accession Number mRNA
BC031782
Chromosomal Location
13 A2
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
93.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Elmo1
Species
Mouse
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/140580
Uniprot URL
https://www.uniprot.org/uniprot/Q8BPU7
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/BC031782

UniProtKB · Q8BPU7

Engulfment and cell motility protein 1

ELMO1_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
Q8BPU7
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Elmo1
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q8BSY9, Q8K2C5, Q91ZU3
Protein keywords

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Biological process

ApoptosisPhagocytosis

Cellular component

Cell membraneCytoplasmMembrane

Technical term

Reference proteome

Domain

SH3-binding