ELMO1 (NM_014800) Human Recombinant Protein

• Background:

  This gene encodes a member of the engulfment and cell motility protein family. These proteins interact with dedicator of cytokinesis proteins to promote phagocytosis and cell migration. Increased expression of this gene and dedicator of cytokinesis 1 may promote glioma cell invasion, and single nucleotide polymorphisms in this gene may be associated with diabetic nephropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

• Synonyms:

  CED-12; CED12; ELMO-1

• Gene ID:

  9844

• UniProt:

  Q92556, A4D1X5

• Accession Number mRNA:

  NM_014800

• Chromosomal Location:

  7p14.2-p14.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Chemokine signaling pathway

• Field of Research:

  Chemokine signaling pathway

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  83.6 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  ELMO1

• Species:

  Human

• Protein ID:

  NP_055615

• Overview:

  Recombinant protein of human engulfment and cell motility 1 (ELMO1), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/9844

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q92556

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_014800

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_055615