Acvrl1 (NM_009612) Mouse Recombinant Protein

• Background:

  Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  Acvrlk1; AI115505; AI427544; Alk1

• Gene ID:

  11482

• UniProt:

  Q61288

• Accession Number mRNA:

  NM_009612

• Chromosomal Location:

  15 F1

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  56.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Acvrl1

• Species:

  Mouse

• Protein ID:

  NP_033742

• Overview:

  Purified recombinant protein of Mouse activin A receptor, type II-like 1 (Acvrl1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/11482

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q61288

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_009612

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_033742