ACVRL1 Antibody (N-term) [APR06982G]

• Synonyms:

  Serine/threonine-protein kinase receptor R3, SKR3, Activin receptor-like kinase 1, ALK-1, TGF-B superfamily receptor type I, TSR-I, ACVRL1, ACVRLK1, ALK1

• Gene Name:

  ACVRL1

• Gene ID:

  94

• UniProt:

  P37023

• Chromosomal Location:

  Cell membrane; Single-pass type I membrane protein

• Applications:

  WB, FC, IHC-P

• Dilution:

  WB--1:1000 FC--1:10~50 IHC-P--1:100~500

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

• Function:

  Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.

• Molecular Weight:

  56124

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ACVRL1 Antibody (N-term) [APR06982G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=94

• Uniprot URL:

  https://www.uniprot.org/uniprot/P37023