ACVRL1 Mouse Monoclonal Antibody [Clone ID: LBI5C2]

• Background:

  This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. [provided by RefSeq, Jul 2008]

• Synonyms:

  ACVRLK1; ALK-1; ALK1; HHT; HHT2; ORW2; SKR3; TSR-I

• Gene Name:

  Homo sapiens activin A receptor like type 1 (ACVRL1), transcript variant 1, mRNA.

• Gene ID:

  94

• UniProt:

  P37023

• Conjugation:

  Unconjugated

• Related Pathways:

  Cytokine-cytokine receptor interaction, TGF-beta signaling pathway

• Field of Research:

  Cytokine-cytokine receptor interaction, TGF-beta signaling pathway

• Dilution:

  WB 1:500~2000

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Function:

  Druggable Genome, Protein Kinase, Transmembrane

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  ACVRL1

• Overview:

  Carrier-free (BSA/glycerol-free) ACVRL1 mouse monoclonal antibody, clone LBI5C2

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=94

• Uniprot URL:

  https://www.uniprot.org/uniprot/P37023