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Wdr48 (BC048155) Mouse Recombinant Protein

CAT: 0882-PM45342M5Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0882-PM45342M5Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Regulator of deubiquitinating complexes. Acts as a strong activator of USP1 and USP46. Enhances the USP1-mediated deubiquitination of FANCD2; USP1 being almost inactive by itself. Also activates deubiquitinating activity of complexes containing USP12. Activates deubiquitination by increasing the catalytic turnover without increasing the affinity of deubiquitinating enzymes for the substrate.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse WD repeat domain 48 (cDNA clone MGC:61205 IMAGE:5698339), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
8430408H12Rik; mKIAA1449; Uaf1
Gene ID
67561
UniProt
Q8BH57
Accession Number mRNA
BC048155
Chromosomal Location
9 F4
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
74.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Wdr48
Species
Mouse
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/67561
Uniprot URL
https://www.uniprot.org/uniprot/Q8BH57
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/BC048155

UniProtKB · Q8BH57

WD repeat-containing protein 48

WDR48_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
Q8BH57
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Wdr48
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q80TD4, Q80XI0, Q8BRM0, Q8CBK0, Q922Z9, Q9CRR1, Q9CSL0
Protein keywords

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmEndosomeLysosomeNucleus

Biological process

DNA damageDNA repairUbl conjugation pathway

Molecular function

DNA-binding

Technical term

Reference proteome

Domain

RepeatWD repeat

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