Tgm3 (NM_009374) Mouse Recombinant Protein

• Background:

  Catalyzes the calcium-dependent formation of isopeptide cross-links between glutamine and lysine residues in various proteins, as well as the conjugation of polyamines to proteins. Involved in the formation of the cornified envelope (CE), a specialized component consisting of covalent cross-links of proteins beneath the plasma membrane of terminally differentiated keratinocytes. Catalyzes small proline-rich proteins (SPRR1 and SPRR2) and LOR cross-linking to form small interchain oligomers, which are further cross-linked by TGM1 onto the growing CE scaffold (By similarity) . In hair follicles, involved in cross-linking structural proteins to hardening the inner root sheath.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  AI893889; TG (E) ; TGase-3; TGase E; TG E; TGE; we

• Gene ID:

  21818

• UniProt:

  Q08189

• Accession Number mRNA:

  NM_009374

• Chromosomal Location:

  2 F1

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  77.3 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Tgm3

• Species:

  Mouse

• Protein ID:

  NP_033400

• Overview:

  Purified recombinant protein of Mouse transglutaminase 3, E polypeptide (Tgm3), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/21818

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q08189

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_009374

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_033400