Transglutaminase 3 (TGM3) (NM_003245) Human Recombinant Protein

• Background:

  Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene consists of two polypeptide chains activated from a single precursor protein by proteolysis. The encoded protein is involved the later stages of cell envelope formation in the epidermis and hair follicle. [provided by RefSeq, Jul 2008]

• Synonyms:

  TGE; UHS2

• Gene ID:

  7053

• UniProt:

  Q08188

• Accession Number mRNA:

  NM_003245

• Chromosomal Location:

  20p13

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  76.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  TGM3

• Species:

  Human

• Protein ID:

  NP_003236

• Overview:

  Recombinant protein of human transglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase) (TGM3)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/7053

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q08188

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_003245

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_003236