Runx1t1 (NM_001111026) Mouse Recombinant Protein

• Background:

  Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes. Can repress the expression of MMP7 in a ZBTB33-dependent manner. Can repress transactivation mediated by TCF12 (By similarity) . Acts as a negative regulator of adipogenesis (PubMed:23527555) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  Cbfa2t1h; ETO; MTG8

• Gene ID:

  12395

• UniProt:

  Q3UQX8, Q8C066

• Accession Number mRNA:

  NM_001111026

• Chromosomal Location:

  4 5.88 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  65.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Runx1t1

• Species:

  Mouse

• Protein ID:

  NP_001104496

• Overview:

  Purified recombinant protein of Mouse RUNX1 translocation partner 1 (Runx1t1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/12395

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q3UQX8

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001111026

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001104496