Stat4 (NM_011487) Mouse Recombinant Protein

• Background:

  The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. Homozygous knockout mice for this gene exhibit reduced inflammation and cytokine production in response to immune challenge. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

• Gene ID:

  20849

• UniProt:

  P42228, Q3V157

• Accession Number mRNA:

  NM_011487

• Chromosomal Location:

  1 26.67 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  85.8 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Stat4

• Species:

  Mouse

• Protein ID:

  NP_035617

• Overview:

  Purified recombinant protein of Mouse signal transducer and activator of transcription 4 (Stat4), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/20849

• Uniprot URL:

  https://www.uniprot.org/uniprot/P42228

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_011487

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_035617