STAT4 Mouse Monoclonal Antibody [Clone ID: LBI4H6]

• Background:

  The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug

• Synonyms:

  SLEB11

• Gene Name:

  Homo sapiens signal transducer and activator of transcription 4 (STAT4), transcript variant 1, mRNA.

• Gene ID:

  6775

• UniProt:

  Q14765

• Conjugation:

  Unconjugated

• Related Pathways:

  Jak-STAT signaling pathway

• Field of Research:

  Jak-STAT signaling pathway

• Dilution:

  WB 1:2000, IHC 1:150, FLOW 1:100

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Function:

  Druggable Genome, Transcription Factors

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  STAT4

• Overview:

  Carrier-free (BSA/glycerol-free) STAT4 mouse monoclonal antibody, clone LBI4H6

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=6775

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q14765