Unc13d (NM_001009573) Mouse Recombinant Protein

• Background:

  Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse. Regulates assembly of recycling and late endosomal structures, leading to the formation of an endosomal exocytic compartment that fuses with perforin-containing granules at the immunologic synapse and licences them for exocytosis (By similarity) . Regulates Ca (2+) -dependent secretory lysosome exocytosis in mast cells.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  2610108D09Rik; Jinx; mFLJ00067; Munc13-4

• Gene ID:

  70450

• UniProt:

  B2RUP2, Q80UG7

• Accession Number mRNA:

  NM_001009573

• Chromosomal Location:

  11 E2

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  122.9 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Unc13d

• Species:

  Mouse

• Protein ID:

  NP_001009573

• Overview:

  Purified recombinant protein of Mouse unc-13 homolog D (Unc13d), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/70450

• Uniprot URL:

  https://www.uniprot.org/uniprot/B2RUP2

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001009573

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001009573