Munc 13 4 (UNC13D) Mouse Monoclonal Antibody [Clone ID: LBI1F4]

• Background:

  This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder. [provided by RefSeq, Jul 2008]

• Synonyms:

  FHL3; HLH3; HPLH3; Munc13-4

• Gene Name:

  Homo sapiens unc-13 homolog D (UNC13D), mRNA.

• Gene ID:

  201294

• UniProt:

  Q70J99

• Conjugation:

  Unconjugated

• Dilution:

  WB 1:200~1000

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  UNC13D

• Overview:

  Carrier-free (glycerol/BSA-free) UNC13D mouse monoclonal antibody, clone LBI1F4

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=201294

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q70J99