Il17a (NM_010552) Mouse Recombinant Protein

• Background:

  This gene encodes a pro-inflammatory cytokine that is a member of the interleukin-17 family. The encoded protein plays a central role in host defense against diverse pathogens. The encoded protein is produced by activated T-cells and certain cell types of innate immune system. The active protein functions as either a homodimer with other interleukin-17 family members and signals through the interleukin-17 receptor to induce inflammatory cytokine production. Aberrant expression of this gene is associated with autoinflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Sep 2015]

• Synonyms:

  Ctl; Ctla; Ctla-8; Ctla8; Il; IL-; IL-17; IL-17A; Il17

• Gene ID:

  16171

• UniProt:

  Q62386, Q544E6

• Accession Number mRNA:

  NM_010552

• Chromosomal Location:

  1 A4

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  17.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Il17a

• Species:

  Mouse

• Protein ID:

  NP_034682

• Overview:

  Purified recombinant protein of Mouse interleukin 17A (Il17a), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/16171

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q62386

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_010552

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_034682