IL17 (IL17A) Mouse Monoclonal Antibody [Clone ID: LBI4E1]

• Background:

  The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO) . High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Jul 2008]

• Synonyms:

  CTLA-8; CTLA8; IL-17; IL-17A; IL17; ILA17

• Gene Name:

  Interleukin 17A

• Gene ID:

  3605

• UniProt:

  Q16552

• Conjugation:

  Unconjugated

• Related Pathways:

  Cytokine-cytokine receptor interaction

• Field of Research:

  Cytokine-cytokine receptor interaction

• Concentration:

  1 mg/ml

• Dilution:

  ELISA 1:5000-10000

• Form:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Buffer:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Function:

  Druggable Genome, Secreted Protein

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  IL17A

• Overview:

  IL-17A mouse monoclonal antibody, clone LBI4E1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=3605

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q16552