ICOS (NM_012092) Human Recombinant Protein

• Background:

  The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation. [provided by RefSeq, Jul 2008]

• Synonyms:

  AILIM; CD278; CVID1

• Gene ID:

  29851

• UniProt:

  Q9Y6W8, Q53QY6

• Accession Number mRNA:

  NM_012092

• Chromosomal Location:

  2q33.2

• Expression System:

  HEK293

• Tag:

  C-Fc/His

• Related Pathways:

  Cell adhesion molecules (CAMs), Primary immunodeficiency, T cell receptor signaling pathway

• Field of Research:

  Cell adhesion molecules (CAMs), Primary immunodeficiency, T cell receptor signaling pathway

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  PBS, pH7.4, 10% glycerol

• Function:

  Secreted Protein, Transmembrane

• Molecular Weight:

  39 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  ICOS

• Species:

  Human

• Protein ID:

  NP_036224

• Overview:

  Purified recombinant protein of human inducible T-cell co-stimulator (ICOS), with C-terminal Fc/His tag, expressed in human cells, 20 µg

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/29851

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9Y6W8

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_012092

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_036224