Kynurenine 3 monooxygenase (KMO) (NM_003679) Human Recombinant Protein

• Background:

  This gene encodes a mitochondrion outer membrane protein that catalyzes the hydroxylation of L-tryptophan metabolite, L-kynurenine, to form L-3-hydroxykynurenine. Studies in yeast identified this gene as a therapeutic target for Huntington disease. [provided by RefSeq, Oct 2011]

• Synonyms:

  DJ317G22.1

• Gene ID:

  8564

• UniProt:

  O15229, A8K693

• Accession Number mRNA:

  NM_003679

• Chromosomal Location:

  1q43

• Expression System:

  Sf9

• Tag:

  C-DDK

• Related Pathways:

  Metabolic pathways, Tryptophan metabolism

• Field of Research:

  Metabolic pathways, Tryptophan metabolism

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  55.6 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  KMO

• Species:

  Human

• Protein ID:

  NP_003670

• Overview:

  Recombinant protein of human kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) (KMO), full length, with C-terminal DDK tag, expressed in sf9, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/8564

• Uniprot URL:

  https://www.uniprot.org/uniprot/O15229

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_003679

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_003670