Products for Research Use Only
RegisterLogin

E2F3 (NM_001949) Human Recombinant Protein

CAT: 0882-PH32067E1Size: 50 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0882-PH32067E1Size:50 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This gene encodes a member of a small family of transcription factors that function through binding of DP interaction partner proteins. The encoded protein recognizes a specific sequence motif in DNA and interacts directly with the retinoblastoma protein (pRB) to regulate the expression of genes involved in the cell cycle. Altered copy number and activity of this gene have been observed in a number of human cancers. There are pseudogenes for this gene on chromosomes 2 and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]
Overview
Purified recombinant protein of Human E2F transcription factor 3 (E2F3), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Synonyms
E2F-3
Gene ID
1871
UniProt
O00716
Accession Number mRNA
NM_001949
Chromosomal Location
6p22.3
Expression System
E. coli
Tag
N-His
Related Pathways
Bladder cancer, Cell cycle, Chronic myeloid leukemia, Glioma, Melanoma, Non-small cell lung cancer, Pancreatic cancer, Pathways in cancer, Prostate cancer, Small cell lung cancer
Field of Research
Bladder cancer, Cell cycle, Chronic myeloid leukemia, Glioma, Melanoma, Non-small cell lung cancer, Pancreatic cancer, Pathways in cancer, Prostate cancer, Small cell lung cancer
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Activity
26639898
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl
Function
Druggable Genome, Transcription Factors
Molecular Weight
49 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
E2F3
Species
Human
Protein ID
NP_001940
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/1871
Uniprot URL
https://www.uniprot.org/uniprot/O00716
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001949
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001940

UniProtKB · O00716

Transcription factor E2F3

E2F3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O00716
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
E2F3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
E2F-3
EC number
—
Processing
—
Secondary accessions
Q15000, Q68DT0, Q9BZ44
Protein keywords

Molecular function

ActivatorDNA-binding

Coding sequence diversity

Alternative splicing

Biological process

Cell cycleTranscriptionTranscription regulation

Cellular component

Nucleus

Technical term

Proteomics identificationReference proteome

Related Products

CatalogName
LH19629VE2F3 (NM_001949) Human Over-expression Lysate
APR31279G-01E2F3 Antibody (Center) [APR31279G]
APR28443N-01E2F3 Rabbit pAb (APR28443N)
PH39123M5MT1F (NM_005949) Human Recombinant Protein
PH38971M5EIF5 (NM_001969) Human Recombinant Protein
PH42060M5DARS1 (NM_001349) Human Recombinant Protein
PH33798M5ENTPD5 (NM_001249) Human Recombinant Protein
PH41189M5MRPL12 (NM_002949) Human Recombinant Protein
PH36664M5CAPNS1 (NM_001749) Human Recombinant Protein
PH41922M5IFIT3 (NM_001549) Human Recombinant Protein

Alternative Products

CatalogName
TP760363E2F3 (NM_001949) Human Recombinant Protein
ARP2794-01Recombinant Human Leptin Human Recombinant Protein
TP727627Human Recombinant Protein
SC110876E2F3 (NM_001949) Human Untagged Clone
LS001871-20ugE2F3 (NM_001949) Human Over-expression Lysate
RC222471E2F3 (NM_001949) Human Tagged ORF Clone
HP205713E2F3 Human qPCR Primer Pair (NM_001949)
SC220669E2F3 (NM_001949) Human 3' UTR Clone
HK209017E2F3 Human qPCR Template Standard (NM_001949)
RC222471L3E2F3 (NM_001949) Human Tagged Lenti ORF Clone

Popular Products