EIF5A2 Rabbit pAb (APR25615N)

CAT: 0882-APR25615N-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-APR25615N-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

MRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation (By similarity.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality EIF5A2 Rabbit pAb (APR25615N) .

Synonyms

EIF5A2; EIF-5A2; eIF5AII

Gene ID

56648

UniProt

Q9GZV4

Cellular Locus

Cytoplasm, Cytoplasmic side, Endoplasmic reticulum membrane, Nucleus, Peripheral membrane protein, nuclear pore complex

Dilution

WB 1:200 - 1:2000

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 16kDa Observed MW: 17kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=56648

Uniprot URL

https://www.uniprot.org/uniprot/Q9GZV4

AA Sequence

MADEIDFTTGDAGASSTYPMQCSALRKNGFVVLKGRPCKIVEMSTSKTGKHGHAKVHLVGIDIFTGKKYEDICPSTHNMDVPNIKRNDYQLICIQDGYLSLLTETGEVREDLKLPEGELGKEIEGKYNAGEDVQVSVMCAMSEEYAVAIKPCK

UniProtKB · Q9GZV4

Eukaryotic translation initiation factor 5A-2

IF5A2_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q9GZV4
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: EIF5A2
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: eIF-5A-2, eIF-5A2
EC number: —
Processing: —
Secondary accessions: B2R4V5

Protein keywords

PTM

AcetylationHypusine

Cellular component

CytoplasmEndoplasmic reticulumMembraneNucleus

Molecular function

Elongation factorRNA-binding

Biological process

Protein biosynthesis

Technical term

Proteomics identificationReference proteome

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