EIF5A/eIF5A2 rabbit pAb

• Synonyms:

  Eukaryotic translation initiation factor 5A-1 (eIF-5A-1;eIF-5A1;Eukaryotic initiation factor 5A isoform 1;eIF-5A;Rev-binding factor;eIF-4D)

• Gene ID:

  1984

• UniProt:

  P63241/Q9GZV4

• Cellular Locus:

  Cytoplasm. Nucleus. Endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side. Hypusine modification promotes the nuclear export and cytoplasmic localization and there was a dynamic shift in the localization from predominantly cytoplasmic to primarily nuclear under apoptotic inducing conditions (PubMed:19379712, PubMed:27306458). Nuclear export of hypusinated protein is mediated by XPO4 (PubMed:10944119, PubMed:27306458)..

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Synthesized peptide derived from human eIF5A/eIF5A2

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB, ELISA

• Validated Applications:

  WB, ELISA

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-2000, ELISA (peptide) 1:5000-20000

• Molecular Weight:

  17kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  17 kD

• Subcellular Location:

  Cytoplasm . Nucleus . Endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side . Hypusine modification promotes the nuclear export and cytoplasmic localization and there was a dynamic shift in the localization from predominantly cytoplasmic to primarily nuclear under apoptotic inducing conditions (PubMed:19379712, PubMed:27306458) . Nuclear export of hypusinated protein is mediated by XPO4 (PubMed:10944119, PubMed:27306458) . .

• Other Product Names:

  Eukaryotic translation initiation factor 5A-1 (eIF-5A-1; eIF-5A1; Eukaryotic initiation factor 5A isoform 1; eIF-5A; Rev-binding factor; eIF-4D)

• Gene ID (Human):

  1984

• SwissProt (Human):

  P63241/Q9GZV4