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IGF2BP2/IMP2 Rabbit pAb (APR23949N)

CAT: 0882-APR23949N-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0882-APR23949N-01Size:50 µL
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Background
This gene encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternative promoter usage and alternate splicing result in multiple variants encoding different isoforms.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IGF2BP2/IMP2 Rabbit pAb (APR23949N) .
Synonyms
IGF2BP2; IMP-2; IMP2; VICKZ2
Gene ID
10644
UniProt
Q9Y6M1
Cellular Locus
Cytoplasm, Nucleus
Dilution
WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 54kDa/58kDa/59kDa/61kDa/66kDa Observed MW: 70kDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=10644
Uniprot URL
https://www.uniprot.org/uniprot/Q9Y6M1
AA Sequence
TVEACASAEIEIMKKLREAFENDMLAVNQQANLIPGLNLSALGIFSTGLSVLSPPAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQKYPQGVASQRSK

UniProtKB · Q9Y6M1

Insulin-like growth factor 2 mRNA-binding protein 2

IF2B2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9Y6M1
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IGF2BP2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
IGF2 mRNA-binding protein 2, IMP-2
EC number
—
Processing
—
Secondary accessions
A0A4Z0, B3FTN2, B3FTN3, B3FTN4
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative initiationAlternative splicing

Cellular component

CytoplasmNucleus

Biological process

mRNA transportTranslation regulationTransport

Domain

Repeat

Molecular function

RNA-binding