HDAC7 Rabbit pAb (APR23128N)

CAT: 0882-APR23128N-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-APR23128N-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HDAC7 Rabbit pAb (APR23125N2) .

Synonyms

HDAC7; HD7; HD7A; HDAC7A

Gene ID

51564

UniProt

Q8WUI4

Cellular Locus

Cytoplasm, Nucleus

Dilution

IHC 1:50 - 1:200 IF 1:50 - 1:200

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 46-66kDa, 99-108kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=51564

Uniprot URL

https://www.uniprot.org/uniprot/Q8WUI4

AA Sequence

LPPSATAPPPPGPMQPRLEQLKTHVQVIKRSAKPSEKPRLRQIPSAEDLETDGGGPGQVVDDGLEHRELGHGQPEARGPAPLQQHPQVLLWEQQRLAGRLP

UniProtKB · Q8WUI4

Histone deacetylase 7

HDAC7_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q8WUI4
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: HDAC7
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: HD7
EC number: 3.5.1.98
Processing: —
Secondary accessions: B3KY08, B4DWI0, B4E0Q5, Q6P1W9, Q6W9G7, Q7Z4K2, Q7Z5I1, Q96K01, Q9BR73, Q9H7L0, Q9NW41, Q9NWA9, Q9NYK9, Q9UFU7

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Molecular function

Chromatin regulatorHydrolaseRepressor

Cellular component

CytoplasmNucleus

Ligand

Metal-bindingZinc

PTM

Phosphoprotein

Domain

Repeat

Biological process

TranscriptionTranscription regulation

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