NIRF (UHRF2) Mouse Monoclonal Antibody [Clone ID: LBI1H2]

• Background:

  This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding. [provided by RefSeq, Feb 2012]

• Synonyms:

  NIRF; RNF107; TDRD23; URF2

• Gene Name:

  Homo sapiens ubiquitin like with PHD and ring finger domains 2 (UHRF2), transcript variant 1, mRNA.

• Gene ID:

  115426

• UniProt:

  Q96PU4

• Conjugation:

  Unconjugated

• Dilution:

  WB 1:500~2000

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Function:

  Druggable Genome, Transcription Factors

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  UHRF2

• Overview:

  Carrier-free (BSA/glycerol-free) UHRF2 mouse monoclonal antibody, clone LBI1H2

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=115426

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q96PU4