B7H3 (CD276) Mouse Monoclonal Antibody [Clone ID: LBI1A10]

• Background:

  The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].

• Synonyms:

  4Ig-B7-H3; B7-H3; B7H3; B7RP-2

• Gene Name:

  CD276 molecule

• Gene ID:

  80381

• UniProt:

  Q5ZPR3

• Conjugation:

  Unconjugated

• Related Pathways:

  Cell adhesion molecules (CAMs)

• Field of Research:

  Cell adhesion molecules (CAMs)

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:500-1000, FLOW 1:100

• Form:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Buffer:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Function:

  Druggable Genome, Transmembrane

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  CD276

• Overview:

  CD276 mouse monoclonal antibody, clone LBI1A10

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=80381

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q5ZPR3