2′,3′-Didehydro-2′,3′-dideoxy-5-fluorouridine

2′,3′-Didehydro-2′,3′-dideoxy-5-fluorouridine

• CAS Number: 15379-29-0
• UNSPSC Description: 2′,3′-Didehydro-2′,3′-dideoxy-5-fluorouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/2-3-didehydro-2-3-dideoxy-5-fluorouridine.html
• Solubility: 10 mM in DMSO
• Smiles: OC[C@@H]1C=C[C@H](N(C(N2)=O)C=C(F)C2=O)O1
• Molecular Weight: 228.18
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported