CYP11A1 Antibody - middle region: HRP (ARP51906_P050-HRP)

• Gene Name:

  Cytochrome P450 family 11 subfamily A member 1

• Gene Aliases:

  CYP11A, CYPXIA1, P450SCC

• Gene ID:

  1583

• Swiss Prot:

  P05108-2

• Accession Number:

  NP_001093243

• Host:

  Rabbit

• Reactivity:

  Human, Pig, Rabbit

• Immunogen:

  The immunogen is a synthetic peptide directed towards the middle region of Human CP11A

• Target:

  This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide.

• Partner Proteins:

  SMAD9; SMAD3; SMAD2; CYP11B2; FDX1

• Clonality:

  Polyclonal

• Conjugation:

  HRP: Horseradish Peroxidase

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity purified

• Concentration:

  0.5 mg/mL

• Homology:

  Human: 100%; Pig: 75%; Rabbit: 83%

• Format:

  Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  39kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  363

• NCBI Gene Symbol:

  CYP11A1

• Protein Name:

  Cholesterol side-chain cleavage enzyme, mitochondrial