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CYP11A1 Antibody

CAT: 0223-63-278Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-63-278Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CYP11A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones.
NCBI Gene ID
1583
Swiss Prot
P05108
Accession Number
P05108
Host
Rabbit
Reactivity
Human
Immunogen
This CYP11A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-120 amino acids from the N-terminal region of human CYP11A1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Monkey
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
60 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CYP11A1
NCBI Official Name
Cholesterol side-chain cleavage enzyme, mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Celhar, T., Cancer Genet. Cytogenet. 187 (1), 28-33 (2008)
Background Reference 02
Morales, A., Pancreas 37 (2), 165-169 (2008)
Background Reference 03
Shigematsu, K., Eur. J. Endocrinol. 158 (6), 867-878 (2008)
Other Product Names
Cholesterol side-chain cleavage enzyme, mitochondrial, CYPXIA1, Cholesterol desmolase, Cytochrome P450 11A1, Cytochrome P450 (scc), CYP11A1, CYP11A
Tested Applications
WB
Protein ID
143811381
Physical Properties
Liquid

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