Interleukin-1 alpha (IL-1A, Human Recombinant)

• Description:

  Interleukin-1 alpha (IL-1A, Human Recombinant)_x000D_ Catalog number: B2010264_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Volume/Weight: 10 ug_x000D_ pH: n/a_x000D_ Supplied as: Reconstitute before use_x000D_ Appearance: Solid_x000D_ Applications: highly pure recombinant human Interleukin 1 alpha (expressed in E. coli). IL-1 alpha a non-glycosylated 159 amino residues protein with a MW of 18 kDa._x000D_ Storage: -20C_x000D_ Keywords: rHuIL-1α; Hematopoietin-1; IL1A; IL1F1; IL-1 alpha_x000D_ Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through0.22 um._x000D_ _x000D_ References:_x000D_ 1: Bou-Dargham MJ, Khamis ZI, Cognetta AB, Sang QA. The Role of Interleukin-1 in_x000D_ Inflammatory and Malignant Human Skin Diseases and the Rationale for Targeting_x000D_ Interleukin-1 Alpha. Med Res Rev. 2017 Jan;37(1):180-216._x000D_ _x000D_ 2: Malik A, Kanneganti TD. Function and regulation of IL-1α in inflammatory_x000D_ diseases and cancer. Immunol Rev. 2018 Jan;281(1):124-137._x000D_ _x000D_ 3: Di Paolo NC, Shayakhmetov DM. Interleukin 1α and the inflammatory process._x000D_ Nat Immunol. 2016 Jul 19;17(8):906-13._x000D_ _x000D_ 4: Ghasemi M, Kashani E, Fayyaz A, Attar M, Shahbazi M. Interleukin-1 alpha_x000D_ variation is associated with the risk of developing preeclampsia. Eur J Obstet_x000D_ Gynecol Reprod Biol. 2015 Oct;193:75-8._x000D_ _x000D_ 5: Espinosa-Cotton M, Rodman Iii SN, Ross KA, Jensen IJ, Sangodeyi-Miller K,_x000D_ McLaren AJ, Dahl RA, Gibson-Corley KN, Koch AT, Fu YX, Badovinac VP, Laux D,_x000D_ Narasimhan B, Simons AL. Interleukin-1 alpha increases anti-tumor efficacy of_x000D_ cetuximab in head and neck squamous cell carcinoma. J Immunother Cancer. 2019_x000D_ Mar 19;7(1):79._x000D_ _x000D_ 6: de Mooij CEM, Netea MG, van der Velden WJFM, Blijlevens NMA. Targeting the_x000D_ interleukin-1 pathway in patients with hematological disorders. Blood. 2017 Jun_x000D_ 15;129(24):3155-3164._x000D_ _x000D_ 7: Schultz K, Murthy V, Tatro JB, Beasley D. Endogenous interleukin-1 alpha_x000D_ promotes a proliferative and proinflammatory phenotype in human vascular smooth_x000D_ muscle cells. Am J Physiol Heart Circ Physiol. 2007 Jun;292(6):H2927-34._x000D_ _x000D_ 8: Mendoza-Carrera F, Ramírez-López G, Hernández-Ramos LE, Leal-Cortés C,_x000D_ Portilla-de-Buen E, Castro-Martínez XH, Castro Martínez AG, López-Quintero A,_x000D_ Flores-Martínez SE, Sánchez-Corona J. Interleukin-1 Alpha Polymorphisms Are_x000D_ Associated With Body Mass Index in Male But Not in Female Adolescents. Arch Med_x000D_ Res. 2019 Apr;50(3):151-157._x000D_ _x000D_ 9: Albuquerque C, Morinha F, Magalhães J, Requicha J, Dias I, Guedes-Pinto H,_x000D_ Bastos E, Viegas C. Variants in the interleukin-1 alpha and beta genes, and the_x000D_ risk for periodontal disease in dogs. J Genet. 2015 Dec;94(4):651-9._x000D_ _x000D_ 10: Marchiori LLM, Doi MY, Marchiori GM, de Souza GV, Poli-Frederico RC,_x000D_ Ciquinato DSA. Interleukin-1 alpha gene polymorphism (IL-1α) and susceptibility_x000D_ to tinnitus in the elderly. Noise Health. 2019 Mar-Apr;21(99):77-82._x000D_ _x000D_ 11: Goh YC, Chan SW, Siar CH. Parenchyma-stromal interleukin-1 alpha and_x000D_ interleukin-6 overexpressions in ameloblastoma correlate with the aggressive_x000D_ phenotype. Malays J Pathol. 2019 Dec;41(3):303-311._x000D_ _x000D_ 12: Badie A, Saliminejad K, Salahshourifar I, Khorram Khorshid HR. Interleukin 1_x000D_ alpha (IL1A) polymorphisms and risk of endometriosis in Iranian_x000D_ population: a case-control study. Gynecol Endocrinol. 2020 Feb;36(2):135-138._x000D_ _x000D_ 13: Nakayama Y, Ishikawa C, Tamaki K, Senba M, Fujita J, Mori N. Interleukin-1_x000D_ alpha produced by human T-cell leukaemia virus type I-infected T cells induces_x000D_ intercellular adhesion molecule-1 expression on lung epithelial cells. J Med_x000D_ Microbiol. 2011 Dec;60(Pt 12):1750-1761._x000D_ 14: de Jongh CM, Khrenova L, Kezic S, Rustemeyer T, Verberk MM, John SM._x000D_ Polymorphisms in the interleukin-1 gene influence the stratum corneum_x000D_ interleukin-1 alpha concentration in uninvolved skin of patients with chronic_x000D_ irritant contact dermatitis. Contact Dermatitis. 2008 May;58(5):263-8. _x000D_ _x000D_ Products Related to Human Interleukin-1 alpha (IL-1A) : SARS-CoV-2

• Short Description:

  Catalog Number: B2010264 (10 ug)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5

• Height :

  0.5

• CAS Number:

  9000-83-3