Interleukin-33 (IL-33, Human, Recombinant)

• Description:

  Human Interleukin-33 (IL-33)_x000D_ Catalog number: B2010265_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Volume/Weight: 10 ug_x000D_ pH: n/a_x000D_ Supplied as: Reconstitute before use_x000D_ Appearance: Solid_x000D_ Applications: highly pure recombinant human Interleukin (expressed in E. coli). IL-33 is proinflammatory protein that is homologous (structurally and functionally) to the IL-1 cytokine family of proteins._x000D_ Storage: -20C_x000D_ Keywords: rHuIL-33; IL-1F11; NF-HEV; DVS 27_x000D_ Grade: Biotechnology grade. All components are highly pure (minimum 99%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered on a 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Cayrol C, Girard JP. Interleukin-33 (IL-33): A nuclear cytokine from the IL-1_x000D_ family. Immunol Rev. 2018 Jan;281(1):154-168._x000D_ _x000D_ 2: Tan Z, Liu Q, Jiang R, Lv L, Shoto SS, Maillet I, Quesniaux V, Tang J, Zhang_x000D_ W, Sun B, Ryffel B. Interleukin-33 drives hepatic fibrosis through activation of_x000D_ hepatic stellate cells. Cell Mol Immunol. 2018 Apr;15(4):388-398._x000D_ _x000D_ 3: Yamamoto M, Umebashi K, Tokito A, Imamura J, Jougasaki M. Interleukin-33_x000D_ induces growth-regulated oncogene-α expression and secretion in human umbilical_x000D_ vein endothelial cells. Am J Physiol Regul Integr Comp Physiol. 2017 Sep_x000D_ 1;313(3):R272-R279._x000D_ _x000D_ 4: Huang B, Faucette AN, Pawlitz MD, Pei B, Goyert JW, Zhou JZ, El-Hage NG, Deng_x000D_ J, Lin J, Yao F, Dewar RS 3rd, Jassal JS, Sandberg ML, Dai J, Cols M, Shen C,_x000D_ Polin LA, Nichols RA, Jones TB, Bluth MH, Puder KS, Gonik B, Nayak NR, Puscheck_x000D_ E, Wei WZ, Cerutti A, Colonna M, Chen K. Interleukin-33-induced expression of_x000D_ PIBF1 by decidual B cells protects against preterm labor. Nat Med. 2017_x000D_ Jan;23(1):128-135._x000D_ _x000D_ 5: Tseng CCS, Huibers MMH, van Kuik J, de Weger RA, Vink A, de Jonge N. The_x000D_ Interleukin-33/ST2 Pathway Is Expressed in the Failing Human Heart and_x000D_ Associated with Pro-fibrotic Remodeling of the Myocardium. J Cardiovasc Transl_x000D_ Res. 2018 Feb;11(1):15-21._x000D_ _x000D_ 6: Dalmas E, Lehmann FM, Dror E, Wueest S, Thienel C, Borsigova M, Stawiski M,_x000D_ Traunecker E, Lucchini FC, Dapito DH, Kallert SM, Guigas B, Pattou F, Kerr-Conte_x000D_ J, Maechler P, Girard JP, Konrad D, Wolfrum C, Böni-Schnetzler M, Finke D,_x000D_ Donath MY. Interleukin-33-Activated Islet-Resident Innate Lymphoid Cells Promote_x000D_ Insulin Secretion through Myeloid Cell Retinoic Acid Production. Immunity. 2017_x000D_ Nov 21;47(5):928-942.e7._x000D_ _x000D_ 7: Osbourn M, Soares DC, Vacca F, Cohen ES, Scott IC, Gregory WF, Smyth DJ,_x000D_ Toivakka M, Kemter AM, le Bihan T, Wear M, Hoving D, Filbey KJ, Hewitson JP,_x000D_ Henderson H, Gonzàlez-Cìscar A, Errington C, Vermeren S, Astier AL, Wallace WA,_x000D_ Schwarze J, Ivens AC, Maizels RM, McSorley HJ. HpARI Protein Secreted by a_x000D_ Helminth Parasite Suppresses Interleukin-33. Immunity. 2017 Oct_x000D_ 17;47(4):739-751.e5._x000D_ _x000D_ 8: Stojkovic S, Kaun C, Basilio J, Rauscher S, Hell L, Krychtiuk KA, Bonstingl_x000D_ C, de Martin R, Gröger M, Ay C, Holnthoner W, Eppel W, Neumayer C, Huk I, Huber_x000D_ K, Demyanets S, Wojta J. Tissue factor is induced by interleukin-33 in human_x000D_ endothelial cells: a new link between coagulation and inflammation. Sci Rep._x000D_ 2016 May 4;6:25171._x000D_ _x000D_ Products Related to Human Interleukin-33 (IL-33): COVID-19

• Short Description:

  Catalog Number: B2010265 (10 ug)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5

• Height :

  0.5

• CAS Number:

  9000-83-3