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Biricodar (dicitrate)

CAT: 0804-HY-13574Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-13574Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Biricodar dicitrate (VX 710-3) is the dicitrate salt form of Biricodar. Biricodar dicitrate is an inhibitor for P-glycoprotein and multidrug resistance-associated protein 1 (MRP-1), which increases the accumulation of chemotherapy drugs within cancer cells and shows effective chemosensitizing activity in multidrug resistant cells[1].
CAS Number
174254-13-8
Product Name Alternative
VX 710-3
UNSPSC
12352005
Target
P-glycoprotein
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/biricodar-dicitrate.html
Smiles
O=C([C@H]1N(C(C(C2=CC(OC)=C(OC)C(OC)=C2)=O)=O)CCCC1)OC(CCCC3=CC=CN=C3)CCCC4=CC=CN=C4.O=C(CC(C(O)=O)(O)CC(O)=O)O.O=C(CC(C(O)=O)(O)CC(O)=O)O
Molecular Formula
C46H57N3O21
Molecular Weight
987.95
References & Citations
[1]Shukla S, et al., Improving cancer chemotherapy with modulators of ABC drug transporters. Curr Drug Targets. 2011 May;12 (5) :621-30.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2

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