Products for Research Use Only
RegisterLogin

Biricodar

CAT: 0804-HY-13574A-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-13574A-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Biricodar (VX-710) is a modulator of P-glycoprotein and MRP-1; shows effective chemosensitizing activity in multidrug resistant cells.
CAS Number
159997-94-1
Product Name Alternative
VX-710
UNSPSC
12352005
Target
P-glycoprotein
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Biricodar.html
Purity
99.31
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C([C@H]1N(C(C(C2=CC(OC)=C(OC)C(OC)=C2)=O)=O)CCCC1)OC(CCCC3=CC=CN=C3)CCCC4=CC=CN=C4
Molecular Formula
C34H41N3O7
Molecular Weight
603.71
References & Citations
[1]Minderman H, et al. VX-710 (biricodar) increases drug retention and enhances chemosensitivity in resistant cells overexpressing P-glycoprotein, multidrug resistance protein, and breast cancer resistance protein. Clin Cancer Res. 2004 Mar 1;10 (5) :1826-34.|[2]Yanagisawa T, et al. BIRICODAR (VX-710; Incel) : an effective chemosensitizer in neuroblastoma. Br J Cancer. 1999 Jun;80 (8) :1190-6.|[3]Germann UA, et al. Cellular and biochemical characterization of VX-710 as a chemosensitizer: reversal of P-glycoprotein-mediated multidrug resistance in vitro. Anticancer Drugs. 1997 Feb;8 (2) :125-40.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2

Alternative Products

CatalogName
C01869-01Biricodar
A21464-100Biricodar 100mg
BUP02219-01Biricodar dicitrate
A21464-25Biricodar 25mg
A21464-5Biricodar 5mg
A21464-1Biricodar 1mg
A21464-50Biricodar 50mg
A21464-10Biricodar 10mg
A13533-5Biricodar dicitrate 5mg
A13533-25Biricodar dicitrate 25mg

Popular Products