Clindamycin (hydrochloride monohydrate) (Standard)

Clindamycin (hydrochloride monohydrate) (Standard)

• CAS Number: 58207-19-5
• UNSPSC Description: Clindamycin (hydrochloride monohydrate) (Standard) is the analytical standard of Clindamycin (hydrochloride monohydrate). This product is intended for research and analytical applications. Clindamycin hydrochloride monohydrate is an oral protein synthesis inhibitory agent that has the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin hydrochloride monohydrate resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin hydrochloride monohydrate decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla)[1].
• Target Antigen: Antibiotic; Bacterial
• Type: Reference compound
• Related Pathways: Anti-infection
• Field of Research: Infection; Cancer
• Assay Protocol: https://www.medchemexpress.com/clindamycin-hydrochloride-monohydrate-standard.html
• Smiles: CCC[C@H]1CN(C)[C@H](C(N[C@]([C@@]2([H])O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O)([H])[C@H](C)Cl)=O)C1.[H]Cl.[H]O[H]
• Molecular Weight: 479.46
• References & Citations: [1]Hodille E, et al. Clindamycin suppresses virulence expression in inducible clindamycin-resistant Staphylococcus aureus strains. Ann Clin Microbiol Antimicrob. 2018 Oct 20;17(1):38.
• Shipping Conditions: Room temperature