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BZAD-01

CAT: 0804-HY-121100-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-121100-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BZAD-01 is a potent, selective and orally active inhibitor of NMDA NR2B subunit, with a Ki of 72 nM. BZAD-01 can improve postural asymmetry as well as Apomorphine-induced rotation[1].
CAS Number
[305339-41-7]
UNSPSC
12352005
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bzad-01.html
Purity
99.81
Solubility
DMSO : 100 mg/mL (ultrasonic) |Methanol : 250 mg/mL (ultrasonic)
Smiles
N=C(NCC1=C(C(F)(F)F)C=CC=C1)C2=CC=C(C=C2)OC(F)(F)F
Molecular Formula
C16H12F6N2O
Molecular Weight
362.27
References & Citations
[1]Truong L, et, al. Behavioural effects of a selective NMDA NR1A/2B receptor antagonist in rats with unilateral 6-OHDA+parafascicular lesions. Brain Res Bull. 2009 Feb 16;78 (2-3) :91-6.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NMDA Receptor

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