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GTP-14564

CAT: 0804-HY-110026-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-110026-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GTP-14564 is a tyrosine kinase inhibitor targeting to internal tandem duplication (ITD) and FLT3. GTP-14564 inhibits FLT3 ligand-dependent growth in Ba/F3 leukemia cells[1].
CAS Number
34823-86-4
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
FLT3
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/gtp-14564.html
Purity
99.91
Solubility
DMSO : 125 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
C12=C(NN=C2C3=CC=CC=C3)C4=CC=CC=C4O1
Molecular Formula
C15H10N2O
Molecular Weight
234.25
Precautions
H302, H315, H319
References & Citations
[1]Murata K, et al. Selective cytotoxic mechanism of GTP-14564, a novel tyrosine kinase inhibitor in leukemia cells expressing a constitutively active Fms-like tyrosine kinase 3 (FLT3) . J Biol Chem. 2003 Aug 29;278 (35) :32892-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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