AMPC

• Description:

  AMPC is a potent and effective TFF3 inhibitor. AMPC inhibits cell proliferation, survival, oncogenicity, and CSC-like behaviour in TFF3-positive CMS4 CRC cells. AMPC acts as a potential anti-cancer agent alone or in combination with 5-FU, and can be used for cancer research[1].

• UNSPSC:

  12352005

• Target:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/ampc.html

• Purity:

  99.87

• Solubility:

  DMSO : 115 mg/mL (ultrasonic)

• Smiles:

  N#CC(C1C2=CC=C(C3=CC(C)=C(F)N=C3)C=C2)=C(N)OC(C4=CC=CC=C4O5)=C1C5=O

• Molecular Formula:

  C25H16FN3O3

• Molecular Weight:

  425.41

• References & Citations:

  [1]Ru-Mei Chen, et al. Pharmacological Inhibition of TFF3 Enhances Sensitivity of CMS4 Colorectal Carcinoma to 5-Fluorouracil through Inhibition of p44/42 MAPK. Int J Mol Sci. 2019 Dec 9;20 (24) :6215

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2254434-33-6]