AChE-IN-77

• UNSPSC Description:

  AChE-IN-77 (5d) is a potent AChE and BACE1 inhibitor, with IC50 values of 29.46 µM ans 2.85 µM for AChE and BACE1 in vitro metal chelating ability against Fe3+[1].

• Target Antigen:

  Cholinesterase (ChE)

• Type:

  Reference compound

• Related Pathways:

  Neuronal Signaling

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/ache-in-77.html

• Smiles:

  O=C(C1=NOC(C2=CN(C)C3=C2C=CC=C3)=C1)N/N=C/C4=CC=CC(OC)=C4

• Molecular Weight:

  374.39

• References & Citations:

  [1]Aida Iraji, et al. Synthesis, biological evaluation and molecular modeling studies of methyl indole-isoxazole carbohydrazide derivatives as multi-target anti-Alzheimer's agents. Sci Rep. 2024 Sep 10;14(1):21115.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported